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Acral Dedifferentiated Chondrosarcoma of a Toe PhalanxA Case Report
Adam Levin, MD1; Carol D. Morris, MD, MS1
1 Orthopaedic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Suite A-342, New York, NY 10065. E-mail for C. D. Morris: morrisc@mskcc.org
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Investigation performed at the Orthopaedic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY



Disclosure: None of the authors received payments or services, either directly or indirectly (i.e., via his or her institution), from a third party in support of any aspect of this work. None of the authors, or their institution(s), have had any financial relationship, in the thirty-six months prior to submission of this work, with any entity in the biomedical arena that could be perceived to influence or have the potential to influence what is written in this work. Also, no author has had any other relationships, or has engaged in any other activities, that could be perceived to influence or have the potential to influence what is written in this work. The complete Disclosures of Potential Conflicts of Interest submitted by authors are always provided with the online version of the article.

Copyright © 2014 by The Journal of Bone and Joint Surgery, Inc.
JBJS Case Connector, 2014 Feb 12;4(1):e16 1-5. doi: 10.2106/JBJS.CC.M.00214
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Extract

Dedifferentiated chondrosarcoma accounts for approximately 11% of all chondrosarcoma diagnoses and is associated with a dismal prognosis1-3. Originally described as well-differentiated chondrosarcoma juxtaposed with areas of fibrosarcoma or osteogenic sarcoma4, the diagnosis is now considered when a chondrosarcoma is juxtaposed to another usually high-grade spindle-cell sarcoma. The sex distribution for dedifferentiated chondrosarcoma is nearly equal, with some series demonstrating a male predominance up to 62%. Patients most frequently present in the sixth or seventh decade of life, with a median age of 54.6 to 68.8 years in the largest case series1-3,5-7.
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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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