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Monostotic Fibrous Dysplasia of the Lumbar VertebraA Case Report and Review of the Literature
Bin Yu, MD1; Desheng Wu, MD1; Yan Lin, MD2; Weidong Zhao, MD1; Jianguang Zhu, MD1; Yufeng Huang, MD1; Bin Shen, MD1; Yang Han, MD1; Dongduo Qi, MD1
1 Departments of Spine Surgery (B.Y., D.W., W.Z., J.Z., Y.H., B.S., and D.Q.), and Pathology (Y.H.), East Hospital, Tongji University School of Medicine, 150 Jimo Road, PuDong New Area, Shanghai, 200120, China. E-mail address for B. Yu: yubin200445@sina.com. E-mail address for D. Wu: eastspine@yahoo.com. E-mail address for W. Zhao: zhaospine@126.com. E-mail address for J. Zhu: 13916676766@163.com. E-mail address for Y. Huang: surgeonhng@hotmail.com. E-mail address for B. Shen: sanly621@163.com. E-mail address for Y. Han: ada_hy@sohu.com. E-mail address for D. Qi: qidongduo@gmail.com
2 Department of Orthopedic Surgery, Shanghai Seventh People’s Hospital, 358 Datong Road, PuDong New Area, Shanghai, 200137, China. Email address: ianlynn02@hotmail.com
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Investigation performed at the Departments of Spine Surgery and Pathology, East Hospital, Shanghai, China



Disclosure: None of the authors received payments or services, either directly or indirectly (i.e., via his or her institution), from a third party in support of any aspect of this work. None of the authors, or their institution(s), have had any financial relationship, in the thirty-six months prior to submission of this work, with any entity in the biomedical arena that could be perceived to influence or have the potential to influence what is written in this work. Also, no author has had any other relationships, or has engaged in any other activities, that could be perceived to influence or have the potential to influence what is written in this work. The complete Disclosures of Potential Conflicts of Interest submitted by authors are always provided with the online version of the article.

Copyright © 2013 by The Journal of Bone and Joint Surgery, Inc.
JBJS Case Connector, 2014 Jan 22;4(1):e9 1-6. doi: 10.2106/JBJS.CC.M.00177
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Extract

Fibrous dysplasia (FD) is an uncommon benign fibro-osseous lesion of the bone, characterized by the replacement of normal cancellous bone with fibroblastic tissue that contains irregularly shaped metaplastic woven bone1. This disease has different forms: monostotic (MFD), polyostotic (PFD), or variable with cutaneous and endocrine abnormalities (McCune-Albright syndrome)2. MFD most commonly affects the ribs, femur, tibia, jaws, calvarium, and humerus3,4. Spine involvement in MFD is exceedingly rare, particularly in the lumbar spine. To our knowledge, there have been only fifteen cases of lumbar MFD previously described in the literature4-18. We present a rare case of MFD of the fourth lumbar vertebra and review the relevant literature.
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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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