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Enhanced Callus Formation After Six Weeks of Parathyroid Hormone Treatment in a Man with Multiple Pelvic Fractures and Osteogenesis Imperfecta Type IVA Case Report
Roland Kocijan, MD1; Judith Haschka, MD1; Christian Muschitz, MD1; Angela Trubrich, MD1; Janina Patsch, MD2; Heinrich Resch, MD1
1 Medical Department II, Academic Teaching Hospital of the Medical University of Vienna, VINFORCE Study Group, St. Vincent Hospital, Vienna, Austria, Stumpergasse 13, 1060 Vienna, Austria. E-mail address for R. Kocijan: roland.kocijan@bhs.at
2 Department of Diagnostic Radiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria
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Investigation performed at the VINFORCE Study Group, St. Vincent Hospital, Vienna, Austria



Disclosure: None of the authors received payments or services, either directly or indirectly (i.e., via his or her institution), from a third party in support of any aspect of this work. None of the authors, or their institution(s), have had any financial relationship, in the thirty-six months prior to submission of this work, with any entity in the biomedical arena that could be perceived to influence or have the potential to influence what is written in this work. Also, no author has had any other relationships, or has engaged in any other activities, that could be perceived to influence or have the potential to influence what is written in this work. The complete Disclosures of Potential Conflicts of Interest submitted by authors are always provided with the online version of the article.

Copyright © 2012 by The Journal of Bone and Joint Surgery, Inc.
JBJS Case Connector, 2012 Nov 28;2(4):e74 1-3. doi: 10.2106/JBJS.CC.L.00042
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Extract

Osteogenesis imperfecta (OI) is a genetic disorder involving a defect in collagen synthesis1-3. OI is characterized by impaired bone formation, low bone mass, and deterioration of bone architecture in adults4,5. Typical bone features are a decrease in trabecular thickness and number of trabeculae, as well as thin cortices. As a result, there is increased bone fragility with recurrent fractures, leading frequently to skeletal deformities.
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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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