Case Reports   |    
Bilateral Acute Calcium Pyrophosphate Crystal Arthritis After Bilateral Total Knee ArthroplastyA Case Report
Joshua L. Carter, MD1; Nathan K. Endres, MD1; David A. Halsey, MD2
1 Department of Orthopaedics and Rehabilitation, University of Vermont, Stafford Hall 4th Floor, 95 Carrigan Drive, Burlington, VT 05401. E-mail address for J.L. Carter: joshua.carter@vtmednet.org. E-mail address for N.K. Endres: nathan.endres@med.uvm.edu
2 Orthopedic Specialty Center, 192 Tilley Drive, South Burlington, VT 05403. E-mail address: David.Halsey@vtmednet.org
View Disclosures and Other Information
  • Disclosure statement for author(s): PDF

Investigation performed at Fletcher Allen Health Care, University of Vermont, Burlington, Vermont

Disclosure: None of the authors received payments or services, either directly or indirectly (i.e., via his or her institution), from a third party in support of any aspect of this work. None of the authors, or their institution(s), have had any financial relationship, in the thirty-six months prior to submission of this work, with any entity in the biomedical arena that could be perceived to influence or have the potential to influence what is written in this work. Also, no author has had any other relationships, or has engaged in any other activities, that could be perceived to influence or have the potential to influence what is written in this work. The complete Disclosures of Potential Conflicts of Interest submitted by authors are always provided with the online version of the article.

Copyright © 2012 by The Journal of Bone and Joint Surgery, Inc.
JBJS Case Connector, 2012 Oct 10;2(4):e59 1-4. doi: 10.2106/JBJS.CC.K.00167
5 Recommendations (Recommend) | 3 Comments | Saved by 3 Users Save Case


Calcium pyrophosphate dihydrate (CPPD) deposition disease is a well-described condition of synovial joints that frequently causes major pain and disability1,2. Acute calcium pyrophosphate (CPP) crystal arthritis, commonly called “pseudogout,” refers to the acute attacks of synovitis clinically resembling acute gouty arthropathy and was initially described nearly fifty years ago1,3. The body’s inflammatory response to the crystalline arthropathy causes painful synovitis, and it may bear all of the clinical hallmarks of septic arthritis. The incidence of the disease increases with age, and CPP crystals are commonly found in the synovial fluid aspirates of osteoarthritic knees before total joint arthroplasty4. Cases of CPPD disease, however, have rarely been reported after total joint arthroplasty5-9. To our knowledge, bilateral attacks of pseudogout after bilateral total knee arthroplasty have never been reported in the English-language literature. The patient was informed that data concerning the case would be submitted for publication, and she provided consent.
Figures in this Article

    First Page Preview

    View Large
    First page PDF preview
    Sign In to Your Personal ProfileSign In To Access Full Content
    Not a Subscriber?
    Get online access for 30 days for $35
    New to JBJS Case Connector?
    Sign up for a full subscription to both the print and online editions
    Register for a FREE limited account to get full access to all CME activities, to comment on public articles, or to sign up for alerts.
    Register for a FREE limited account to get full access to all CME activities
    Have a subscription to the print edition?
    Current subscribers to The Journal of Bone & Joint Surgery in either the print or quarterly DVD formats receive free online access to JBJS.org.
    Forgot your password?
    Enter your username and email address. We'll send you a reminder to the email address on record.

    Forgot your username or need assistance? Please contact customer service at subs@jbjs.org. If your access is provided
    by your institution, please contact you librarian or administrator for username and password information. Institutional
    administrators, to reset your institution's master username or password, please contact subs@jbjs.org


    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
    CME Activities Associated with This Article
    Submit a Comment
    Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
    Comments are moderated and will appear on the site at the discretion of JBJS editorial staff.

    * = Required Field
    (if multiple authors, separate names by comma)
    Example: John Doe

    Related Content
    The Journal of Bone & Joint Surgery
    Provided by:
    JBJS Case Connector
    Topic Collections
    Related Audio and Videos
    PubMed Articles
    Clinical Trials
    Readers of This Also Read...
    JBJS Jobs
    Ohio - OhioHealth Research and Innovation Institute (OHRI)
    Pennsylvania - Penn State Milton S. Hershey Medical Center